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As a term, nanotechnology is clearly ambiguous. Moreover, it has already been claimed by the Drexlerians, apostles of K. Eric Drexler, who was one of the first to popularize nanotechnology with the publication of his 1987 book, Engineers of Creation: The Coming Era of Nanotechnology. According to Professor Steve Block, the Drexlerians have a futurist vision of nanotechnology in which self-replicating molecular assemblers programmed at the molecular-scale manufacture arbitrary products at the atomic level, molecule by molecule, bottom up. Some scientists have attempted to distance themselves from the futurist Drexlerians by claiming the term nanoscience. There's also another motivation for the excision of "technology" in this term. Nanoscience, as a term, captures the learning-the fundamental understanding of processes and materials at the nanoscale-that many scientists feel is necessary before or at the same time that researchers turn to engineering solutions. The term nanotechnology, on the other hand, reinforces what Chidsey describes as a "glib attitude" that "technology is the goal of science at this length scale."
To study single molecules, Block has pioneered the use of optical tweezers, tiny laser-based "tractor beams" that produce miniscule piconewton forces to drag around molecules and allow measurements of displacements on the order of a nanometer. "You can stop and stall molecules, w follow their motion. Recently, we've studied the backtracking of RNA polymerase: when it makes a mistake, it can actually back up by five bases, scoop off the wrong thing and start again," says Block. While biological nanotechnology "hasn't even arrived at its infancy yet," says Block, "biological nanoscience is a very exciting place to be right now, because the techniques now exist to truly study proteins, and we're learning so much about them."
Here's To Biology: Nature's Own Nanomachines Dr. Steve Block, Biology and Applied Physics
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